Hazardous material may also be considered dangerous if it threatens safety since it is poisonous, toxic, corrosive, explosive, flammable, etc. The U.S. Department of transportation concerning The Federal Hazardous Materials Law more precisely defined these materials. In the U.S., the term "hazardous materials" is more commonly used for shipments within the country, whereas "dangerous goods" are used for international shipments. It may be necessary to provide special documentation or packaging when shipping hazardous materials.

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